Robust Polytopic-LPV Body-Weight-Dependent Control of Blood Glucose in Type-1 Diabetes

This paper presents a robust H ? polytopic Linear Parameter Varying (LPV) controller to regulate the blood glucose level in type-1 diabetes patients. The suggested approach utilizes an observer-based and inexact gain-scheduling scheme construct stabilizing injecting insulin resilient against external meal snack disturbance Silico. To assure closed-loop stability prescribed performance, Quadratic Lyapunov Function (QLF) is used stabilization conditions are derived terms of Matrix Inequalities (LMIs). conventional minimal Bergman model improved by considering effect body-weight on glucose-insulin phenomenon new functions identified based real data. Then, for body-weight-dependent model, polytopic-LPV obtained. Simulations show advantages developed robustness dealing with effects patients different weights avoiding hypoglycemia hyperglycemia disorders.